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KMID : 1036920170220030197
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Annals of Pediatric Endocrinology & Metabolism
2017 Volume.22 No. 3 p.197 ~ p.202
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A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture
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Song Ji-Yeon
Mun Sue-Jean
Sung Soon-Ki
Hwang Jae-Yeon
Baik Seung-Kug
Kim Jee-Yeon
Cheon Chong-Kun
Kim Su-Young
Kim Yoo-Mi
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Abstract
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Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a left pituitary microadenoma was found. After surgery, transient clinical improvement was observed but headache and hypertension were observed again after 3 months later. Follow-up MRI showed a newly developed right pituitary microadenoma 6 months after the surgery. The need for careful clinical and radiographic follow-up should be emphasized in the search for potential MPAs in patients with persistent Cushing disease.
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KEYWORD
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Adolescent, Cushing disease, Multiple pituitary adenomas, Transsphenoidal surgery
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